A Microfluidics Based 3d Bioprinter with On-the-fly Multimaterial Switching Capability
نویسندگان
چکیده
This work details the development of a novel 3D (3-dimensional) printing system for use in the fabrication of complex biological tissue constructs. The printing system incorporates a microfluidic print head that uses coaxial flow focusing to generate, crosslink, and dispense a microfiber of sodium alginate, and a 3D positioning system to pattern the dispensed microfiber using fused filament fabrication methods, in a software configurable pattern. Valves are embedded in the print-head to enable switching between multiple material sources. Using this system, the composition of the dispensed fiber may be controlled on-the-fly during printing to create complex heterogeneous 3D structures.
منابع مشابه
Microfluidic Printheads for Multimaterial 3D Printing of Viscoelastic Inks.
Multimaterial 3D printing using microfluidic printheads specifically designed for seamless switching between two visco-elastic materials "on-the-fly" during fabrication is demonstrated. This approach opens new avenues for the digital assembly of functional matter with controlled compositional and property gradients at the microscale.
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